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In a statement published on 6 June 2025, the PRAC said it had reviewed “all available data on NAION with semaglutide”, including non-clinical studies, clinical trials, post-marketing surveillance and medical literature
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Despite FLOW and REMODEL not including kidney transplant recipients, it will undoubtedly drive interest in preclinical mechanistic studies elucidating the role of GLP-1RAs in the kidney
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