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It was previously shown that the GLP-1 receptor can control neuronal function in the rat hippocampus by enhancing GABAA signaling through presynaptic and postsynaptic mechanisms (Korol et al., 2015)
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NF-κB, pro-inflammatory cytokines, and VEGF were also shown to be blunted with topical GLP-1 administration in diabetic mice [81]
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