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semaglutide and depression The GLP-1 (#Ozempic) failed to improve mood executive functioning in this, the first RCT of a GLP-1 for major # depression: semaglutide depression risk may reduce –
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Activation of POMC neurons leads to the release of alpha-melanocyte-stimulating hormone (α-MSH), which subsequently binds to the melanocortin 4 receptor in the paraventricular nucleus of the hypothalamus and triggers appetite-inhibiting signaling cascade
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