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The gut and beyond: GI effects and other tissues In the gastrointestinal tract, the receptor appears in the Brunner’s glands of the duodenum, in parietal cells, and in gastric smooth muscle, where it slows gastric emptying

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This is because of the connection between weight and the hypothalamic-pituitary-ovarian axis, according to a 2020 article in The Journal of Clinical Endocrinology and Metabolism