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Short-acting GLP-1RAs like exenatide and lixisenatide are associated with transient (1–12 h) increases, causing a maximum heart rate increase of 8–10 beats per minute (bpm) 2–4 h after injection, which returned to baseline after approximately 10–12 h, with a mean 24 h heart rate increase of approximately 1–2 bpm for both GLP-1RAs in healthy adults ( Linnebjerg et al
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