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Pinch the skin to create a fold, insert the needle at a 90-degree angle for most individuals or a 45-degree angle for very lean individuals, inject slowly, and hold for five seconds after depressing the plunger before withdrawing the needle
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While the MHRA has approved these treatments for adults with a body mass index (BMI) of 30 kg/m² or above, or 27 kg/m² with weight-related comorbidities, it's important to note that NICE guidance (TA875) specifies narrower criteria for NHS access, particularly for semaglutide, which is typically only available through specialist weight management services
