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GLP-1s could gain approval for new uses in 2026, including: Heart failure with preserved ejection fraction (HFpEF): Semaglutide has significant potential for HFpEF among people with a larger body size

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This isn’t a trend — it’s a structural change for the apparel industry.” While GLP-1 usage will directly impact users’ apparel purchasing behavior, footwear brands and retailers can capitalize as well